Mouse Nkap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nkap
Locus ID	67050
Kit Components	GA207109G1, Nkap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207109G2, Nkap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207109G3, Nkap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025937
Synonyms	2610020O08Rik; AA987160; AI849147; AL024236
Summary	Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter (By similarity).[UniProtKB/Swiss-Prot Function]

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