Mouse Riox2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Riox2
Locus ID	67014
Kit Components	GA207083G1, Riox2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207083G2, Riox2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207083G3, Riox2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025910
Synonyms	1810047J07Rik; 2410057H13Rik; 3830408E23Rik; AI449204
Summary	Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39' (By similarity). May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.[UniProtKB/Swiss-Prot Function]

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