Mouse Zdhhc6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zdhhc6
Locus ID	66980
Kit Components	GA207064G1, Zdhhc6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207064G2, Zdhhc6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207064G3, Zdhhc6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033573, NM_025883, NM_001360595
Synonyms	2400007G07Rik; 5930409M18Rik; AI462345; C77369
Summary	Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC (PubMed:25368151). Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (By similarity). Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (By similarity). Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function (PubMed:25368151).[UniProtKB/Swiss-Prot Function]

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