Mouse Trim35 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trim35
Locus ID	66854
Kit Components	GA206991G1, Trim35 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206991G2, Trim35 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206991G3, Trim35 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029979
Synonyms	0710005M05Rik; A430106H13Rik; AW046487; HLS5; Mair; mKIAA1098; NC8
Summary	Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (By similarity). Implicated in the cell death mechanism (PubMed:12692137, PubMed:14662771).[UniProtKB/Swiss-Prot Function]

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