Mouse Rnf220 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf220
Locus ID	66743
Kit Components	GA206935G1, Rnf220 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206935G2, Rnf220 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206935G3, Rnf220 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310729, NM_001310730, NM_001310731, NM_025739
Synonyms	4732477A13; 4931406I20Rik; 5730503K05Rik; AV302541
Summary	E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (PubMed:20170641). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 and promotes Wnt signaling (By similarity).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.