Mouse Brf2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Brf2
Locus ID	66653
Kit Components	GA206888G1, Brf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206888G2, Brf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206888G3, Brf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025686
Synonyms	2700059M06Rik; 5730512K07Rik; AU018504; AU022602; BRFU; TFIIIB50
Summary	General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress.[UniProtKB/Swiss-Prot Function]

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