Mouse Diablo activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Diablo
Locus ID	66593
Kit Components	GA206857G1, Diablo gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206857G2, Diablo gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206857G3, Diablo gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023232
Synonyms	0610041G12Rik; 1700006L01Rik; AU040403; Smac
Summary	Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases (By similarity).[UniProtKB/Swiss-Prot Function]

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