Mouse Drap1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Drap1
Locus ID	66556
Kit Components	GA206839G1, Drap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206839G2, Drap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206839G3, Drap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291080, NM_024176
Synonyms	2310074H19Rik; NC2-alpha
Summary	The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).[UniProtKB/Swiss-Prot Function]

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