Mouse Rtca activation kit by CRISPRa

CAT#: GA206736

Rtca CRISPRa kit - CRISPR gene activation of mouse RNA 3'-terminal phosphate cyclase



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Rtca
Locus ID 66368
Kit Components

GA206736G1, Rtca gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206736G2, Rtca gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206736G3, Rtca gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_025517
Synonyms 2310009A18Rik; AI450277; RPC; Rtcd1
Summary Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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