Mouse Rtca activation kit by CRISPRa
CAT#: GA206736
Rtca CRISPRa kit - CRISPR gene activation of mouse RNA 3'-terminal phosphate cyclase
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Rtca |
Locus ID | 66368 |
Kit Components | GA206736G1, Rtca gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206736G2, Rtca gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206736G3, Rtca gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_025517 |
Synonyms | 2310009A18Rik; AI450277; RPC; Rtcd1 |
Summary | Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN515179 | Rtca - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |