Mouse Cox20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cox20
Locus ID	66359
Kit Components	GA206729G1, Cox20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206729G2, Cox20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206729G3, Cox20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025511
Synonyms	2310005N03Rik; Fam36a
Summary	Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme.[UniProtKB/Swiss-Prot Function]

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