Mouse Cox16 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cox16
Locus ID	66272
Kit Components	GA206680G1, Cox16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206680G2, Cox16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206680G3, Cox16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001309808, NM_001309809, NM_001309810, NM_025461, NR_132134, NR_132135
Synonyms	1810020G14Rik; 1810055I05Rik; BB388670
Summary	Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.[UniProtKB/Swiss-Prot Function]

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