Mouse Sptssb activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sptssb
Locus ID	66183
Kit Components	GA206624G1, Sptssb gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206624G2, Sptssb gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206624G3, Sptssb gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164210, NM_001286959, NM_133675
Synonyms	1110032A04Rik; ADMP; Sssptb
Summary	Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.[UniProtKB/Swiss-Prot Function]

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