Mouse Ifi30 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ifi30
Locus ID	65972
Kit Components	GA206536G1, Ifi30 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206536G2, Ifi30 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206536G3, Ifi30 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023065
Synonyms	GILT; IP30
Summary	Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation.[UniProtKB/Swiss-Prot Function]

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