Mouse Ap3m2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ap3m2
Locus ID	64933
Kit Components	GA206502G1, Ap3m2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206502G2, Ap3m2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206502G3, Ap3m2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001122820, NM_029505
Synonyms	5830445E16Rik; AP-3B
Summary	Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Ap47 is a subunit of the plasma membrane adaptor (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[UniProtKB/Swiss-Prot Function]

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