Mouse Osbpl1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osbpl1a
Locus ID	64291
Kit Components	GA206450G1, Osbpl1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206450G2, Osbpl1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206450G3, Osbpl1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252489, NM_001252490, NM_001252491, NM_001252492, NM_001252493, NM_207530, NR_045524, NM_020573
Synonyms	G430090F17Rik; Gm753; ORP-1; Osbpl1b
Summary	Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol.[UniProtKB/Swiss-Prot Function]

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