Mouse Popdc2 activation kit by CRISPRa
CAT#: GA206433
Popdc2 CRISPRa kit - CRISPR gene activation of mouse popeye domain containing 2
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Popdc2 |
Locus ID | 64082 |
Kit Components | GA206433G1, Popdc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206433G2, Popdc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206433G3, Popdc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001081984, NM_022318 |
Synonyms | AV006127; Pop2 |
Summary | This gene encodes a member of the Popeye domain containing family of membrane proteins. Proteins of this family contain three helical transmembrane domains and a conserved intracellular Popeye domain. In the adult mouse, this gene is expressed at high levels in cardiac myocytes, and mice deficient for this gene develop stress-induced cardiac pacemaker dysfunction. The protein binds to a two-pore domain potassium channel and recruits it to the plasma membrane. Cyclic adenosine monophosphate negatively regulates this interaction through the Popeye domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN513638 | Popdc2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |