Mouse Popdc2 activation kit by CRISPRa

CAT#: GA206433

Popdc2 CRISPRa kit - CRISPR gene activation of mouse popeye domain containing 2



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Popdc2
Locus ID 64082
Kit Components

GA206433G1, Popdc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206433G2, Popdc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206433G3, Popdc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001081984, NM_022318
Synonyms AV006127; Pop2
Summary This gene encodes a member of the Popeye domain containing family of membrane proteins. Proteins of this family contain three helical transmembrane domains and a conserved intracellular Popeye domain. In the adult mouse, this gene is expressed at high levels in cardiac myocytes, and mice deficient for this gene develop stress-induced cardiac pacemaker dysfunction. The protein binds to a two-pore domain potassium channel and recruits it to the plasma membrane. Cyclic adenosine monophosphate negatively regulates this interaction through the Popeye domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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