Mouse Ube4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ube4b
Locus ID	63958
Kit Components	GA206421G1, Ube4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206421G2, Ube4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206421G3, Ube4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022022
Synonyms	4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; mKIAA0684; UFD2; UFD2a; Ufd2p
Summary	Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases (PubMed:11435423). May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase (By similarity). May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function]

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