Mouse Erbin activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Erbin
Locus ID	59079
Kit Components	GA206364G1, Erbin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206364G2, Erbin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206364G3, Erbin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001005868, NM_001289473, NM_001289474, NM_001289475, NM_021563
Synonyms	1700028E05Rik; Erbb2ip; mKIAA1225
Summary	Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ERBB2 'Tyr-1248' receptor, it may contribute to stabilize this unphosphorylated state (By similarity). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728).[UniProtKB/Swiss-Prot Function]

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