Mouse Stard3 activation kit by CRISPRa
CAT#: GA206354
Stard3 CRISPRa kit - CRISPR gene activation of mouse START domain containing 3
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Stard3 |
Locus ID | 59045 |
Kit Components | GA206354G1, Stard3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206354G2, Stard3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206354G3, Stard3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_021547 |
Synonyms | es64; Mln64 |
Summary | Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (By similarity). Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB (By similarity). Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes (By similarity). May also mediate cholesterol transport between other membranes, such as mitochondria membrane or cell membrane (By similarity). However, such results need additional experimental evidences; probably mainly mediates cholesterol transport from the endoplasmic reticulum to endosomes (By similarity). Does not activate transcriptional cholesterol sensing (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN516836 | Stard3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |