Mouse Mkks activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mkks
Locus ID	59030
Kit Components	GA206343G1, Mkks gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206343G2, Mkks gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206343G3, Mkks gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001141946, NM_001286981, NM_001286983, NM_021527
Synonyms	1300013E18Rik; AI463362; AI957237; Bbs6
Summary	This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Alternatively spliced transcripts encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

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