Mouse Edf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Edf1
Locus ID	59022
Kit Components	GA206336G1, Edf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206336G2, Edf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206336G3, Edf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021519
Synonyms	0610008L11Rik; AA409425
Summary	Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. Might function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism (By similarity).[UniProtKB/Swiss-Prot Function]

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