Mouse Anapc5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Anapc5
Locus ID	59008
Kit Components	GA206328G1, Anapc5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206328G2, Anapc5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206328G3, Anapc5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042491, NM_001289517, NM_001289518, NM_001289519, NM_001289520, NM_021505
Synonyms	2510006G12Rik; AA408751; AA536819; AA986414; Anpc5; APC5
Summary	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).[UniProtKB/Swiss-Prot Function]

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