Mouse Cnot9 activation kit by CRISPRa
CAT#: GA206253
Cnot9 CRISPRa kit - CRISPR gene activation of mouse CCR4-NOT transcription complex, subunit 9
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Cnot9 |
Locus ID | 58184 |
Kit Components | GA206253G1, Cnot9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206253G2, Cnot9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206253G3, Cnot9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_021383 |
Synonyms | 2610007F23Rik; AI593551; Fl10; Rqcd1 |
Summary | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation. Required for retinoic acid-induced differentiation of F9 teratocarcinoma cells. Does not bind DNA by itself. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors. May play a role in cell differentiation.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN515127 | Cnot9 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |