Mouse Sertad2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sertad2
Locus ID	58172
Kit Components	GA206247G1, Sertad2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206247G2, Sertad2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206247G3, Sertad2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001038625, NM_021372, NM_001362867
Synonyms	AB041541; AU021878; Kiaa0127; mKIAA0127; MNCb-1504; SEI-2; Sei2; TRIP-Br2
Summary	Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism.[UniProtKB/Swiss-Prot Function]

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