Mouse As3mt activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	As3mt
Locus ID	57344
Kit Components	GA206171G1, As3mt gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206171G2, As3mt gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206171G3, As3mt gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020577
Synonyms	2310045H08Rik; Cyt19
Summary	Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.[UniProtKB/Swiss-Prot Function]

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