Mouse Parva activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Parva
Locus ID	57342
Kit Components	GA206170G1, Parva gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206170G2, Parva gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206170G3, Parva gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020606
Synonyms	2010012A22Rik; 5430400F08Rik; Actp; AI225929; AU042898; CH-ILKBP; Parvin
Summary	Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration. Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development.[UniProtKB/Swiss-Prot Function]

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