Mouse Necab3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Necab3
Locus ID	56846
Kit Components	GA206109G1, Necab3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206109G2, Necab3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206109G3, Necab3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021546
Synonyms	2900010M17Rik; AI853434; Apba2bp; Nip1; XB51
Summary	Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity). May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3 (By similarity).[UniProtKB/Swiss-Prot Function]

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