Mouse Chst5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chst5
Locus ID	56773
Kit Components	GA206089G1, Chst5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206089G2, Chst5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206089G3, Chst5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019950
Synonyms	AI173964; Gn6st-3; GST-4; I-GlcNAc-6-ST
Summary	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures. May also have activity toward O-linked sugars of mucin-type acceptors.[UniProtKB/Swiss-Prot Function]

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