Mouse Rec8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rec8
Locus ID	56739
Kit Components	GA206074G1, Rec8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206074G2, Rec8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206074G3, Rec8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020002, NM_001360389, NM_001360390
Synonyms	mrec; Rec8L1
Summary	Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.[UniProtKB/Swiss-Prot Function]

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