Mouse Rgs19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs19
Locus ID	56470
Kit Components	GA205993G1, Rgs19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205993G2, Rgs19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205993G3, Rgs19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291205, NM_001291206, NM_001291207, NM_001291208, NM_001291209, NM_001291210, NM_026446
Synonyms	2610042F04Rik; AI324841; AW547781; GAIP
Summary	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity).[UniProtKB/Swiss-Prot Function]

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