Mouse Pus1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pus1
Locus ID	56361
Kit Components	GA205922G1, Pus1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205922G2, Pus1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205922G3, Pus1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025561, NM_001025562, NM_001347390, NM_019700, NM_001359218, NM_001359219
Synonyms	A730013B20Rik; MPUS1; mPus1p
Summary	Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA (PubMed:10094309). Involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA (PubMed:15327771). Isoforms 3 and 4 do not form pseudouridine when expressed in vitro (PubMed:11085940).[UniProtKB/Swiss-Prot Function]

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