Mouse Net1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Net1
Locus ID	56349
Kit Components	GA205917G1, Net1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205917G2, Net1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205917G3, Net1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001047159, NM_019671
Synonyms	mNET1; Net1a
Summary	Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway. Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.[UniProtKB/Swiss-Prot Function]

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