Mouse Mad2l1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mad2l1
Locus ID	56150
Kit Components	GA205841G1, Mad2l1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205841G2, Mad2l1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205841G3, Mad2l1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019499, NM_001355624
Synonyms	AA673185; MAD2
Summary	Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate (By similarity).[UniProtKB/Swiss-Prot Function]

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