Mouse Astn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Astn2
Locus ID	56079
Kit Components	GA205830G1, Astn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205830G2, Astn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205830G3, Astn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019514, NM_207109
Synonyms	1d8; Astnl; bM452J22.1
Summary	Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (PubMed:20573900). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (By similarity).[UniProtKB/Swiss-Prot Function]

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