Mouse Usp27x activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Usp27x
Locus ID	54651
Kit Components	GA205754G1, Usp27x gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205754G2, Usp27x gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205754G3, Usp27x gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019461
Synonyms	Sfc11; Usp27
Summary	Deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK-degradation signal. By acting on BCL2L11 levels, may counteract the anti-apoptotic effects of MAPK activity.[UniProtKB/Swiss-Prot Function]

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