Mouse Ccdc120 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccdc120
Locus ID	54648
Kit Components	GA205752G1, Ccdc120 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205752G2, Ccdc120 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205752G3, Ccdc120 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_207202
Synonyms	AA030924; DXImx50e; Jm11; Sfc25
Summary	Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells (PubMed:28422092). Together with CCDC68, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly (PubMed:28422092). Recruits NIN and CEP170 to centrosomes (PubMed:28422092). Also required for neurite growth (By similarity). Localizes CYTH2 to vesicles to allow its transport along neurites, and subsequent ARF6 activation and neurite growth (By similarity).[UniProtKB/Swiss-Prot Function]

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