Mouse Socs6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Socs6
Locus ID	54607
Kit Components	GA205732G1, Socs6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205732G2, Socs6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205732G3, Socs6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018821
Synonyms	1500012M23Rik; 5830401B18Rik; AI447482; Cis4; Cish4; HSPC060; SOCS-4; SOCS-6; Socs4; SSI4; STAI4
Summary	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor (By similarity).[UniProtKB/Swiss-Prot Function]

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