Mouse Unc93b1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Unc93b1
Locus ID	54445
Kit Components	GA205713G1, Unc93b1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205713G2, Unc93b1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205713G3, Unc93b1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001161428, NM_019449
Synonyms	Unc-93B1; Unc93b
Summary	Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.[UniProtKB/Swiss-Prot Function]

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