Mouse Icos activation kit by CRISPRa

CAT#: GA205654

Icos CRISPRa kit - CRISPR gene activation of mouse inducible T cell co-stimulator



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Icos
Locus ID 54167
Kit Components

GA205654G1, Icos gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA205654G2, Icos gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA205654G3, Icos gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_017480
Synonyms AILIM; CCLP; CRP-1; H4; Ly115
Summary Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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