Mouse Icos activation kit by CRISPRa
CAT#: GA205654
Icos CRISPRa kit - CRISPR gene activation of mouse inducible T cell co-stimulator
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Icos |
Locus ID | 54167 |
Kit Components | GA205654G1, Icos gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205654G2, Icos gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205654G3, Icos gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_017480 |
Synonyms | AILIM; CCLP; CRP-1; H4; Ly115 |
Summary | Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN508075 | Icos - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |