Mouse Rasa4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rasa4
Locus ID	54153
Kit Components	GA205650G1, Rasa4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205650G2, Rasa4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205650G3, Rasa4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039103, NM_133914
Synonyms	AA793972; AW112107; BB079060; CAPRI; GAPL
Summary	Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. Isoform 2 activates the Ras pathway and promotes RANKL shedding by modulating the expression of MMP14.[UniProtKB/Swiss-Prot Function]

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