Mouse Gria3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gria3
Locus ID	53623
Kit Components	GA205594G1, Gria3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205594G2, Gria3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205594G3, Gria3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001281929, NM_001290451, NM_016886, NR_104053
Synonyms	2900064I19Rik; GluA3; Glur-3; GluR-C; GluR-K3; Glur3; Gluralpha3
Summary	This gene encodes a multi-pass transmembrane protein that forms a homotetramer or heterotetramer in neuronal cells. The encoded protein is a ligand-gated ion channel that responds to the neurotransmitter L-glutamate to promote synaptic transmission. Deficiency of this gene leads to behavioral phenotypes. The transcript is subject to RNA editing at codon 769 (AGA->GGA; R->G). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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