Mouse Cnot11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cnot11
Locus ID	52846
Kit Components	GA205525G1, Cnot11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205525G2, Cnot11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205525G3, Cnot11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028043
Synonyms	2410015L18Rik; C40; D1Bwg0212e
Summary	Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function (By similarity).[UniProtKB/Swiss-Prot Function]

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