Mouse Tspan14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tspan14
Locus ID	52588
Kit Components	GA205490G1, Tspan14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205490G2, Tspan14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205490G3, Tspan14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001316748, NM_145928
Synonyms	AA958793; D14Ertd226e; Tm4sf14; tspan-14
Summary	Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26668317, PubMed:23035126). Negatively regulates ADAM10-mediated cleavage of GP6 (PubMed:26668317). Promotes ADAM10-mediated cleavage of CDH5 (PubMed:23035126).[UniProtKB/Swiss-Prot Function]

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