Mouse Cdk2ap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdk2ap2
Locus ID	52004
Kit Components	GA205435G1, Cdk2ap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205435G2, Cdk2ap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205435G3, Cdk2ap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026373
Synonyms	5830466O21Rik; D19Ertd144e; Doc-1r
Summary	Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs (PubMed:22548356). Regulates microtubule organization of metaphase II oocytes (PubMed:12944431). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A (By similarity).[UniProtKB/Swiss-Prot Function]

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