Mouse Mcrs1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mcrs1
Locus ID	51812
Kit Components	GA205424G1, Mcrs1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205424G2, Mcrs1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205424G3, Mcrs1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164156, NM_016766
Synonyms	C78274; ICP22BP; MSP58; P78
Summary	Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA. Binds to RNA homopolymer poly(G) and poly(U).[UniProtKB/Swiss-Prot Function]

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