Mouse Tnfsf14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfsf14
Locus ID	50930
Kit Components	GA205404G1, Tnfsf14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205404G2, Tnfsf14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205404G3, Tnfsf14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019418
Synonyms	HVEM-L; HVEML; LIGHT; LTg; Ly113; Tnlg1d
Summary	Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (By similarity).[UniProtKB/Swiss-Prot Function]

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