Mouse Olig2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Olig2
Locus ID	50913
Kit Components	GA205396G1, Olig2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205396G2, Olig2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205396G3, Olig2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_016967
Synonyms	AI604895; Bhlhb1; bHLHe19; Olg-2; Oligo2; RK17
Summary	Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain (PubMed:11955448, PubMed:12121626, PubMed:16908628). Functions together with ZNF488 to promote oligodendrocyte differentiation (PubMed:16908628). Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube (PubMed:11955448, PubMed:12121626). Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (PubMed:11955448, PubMed:12121626).[UniProtKB/Swiss-Prot Function]

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