Mouse Rgs3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs3
Locus ID	50780
Kit Components	GA205360G1, Rgs3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205360G2, Rgs3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205360G3, Rgs3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081650, NM_001310706, NM_019492, NM_134257
Synonyms	4930506N09Rik; C2pa; C2PA-RGS3; PDZ-RGS3; RGS3S
Summary	Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.[UniProtKB/Swiss-Prot Function]

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