Mouse Rgs1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs1
Locus ID	50778
Kit Components	GA205358G1, Rgs1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205358G2, Rgs1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205358G3, Rgs1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015811
Synonyms	BL34
Summary	Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors. Inhibits B cell chemotaxis toward CXCL12 (PubMed:10779778). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (By similarity).[UniProtKB/Swiss-Prot Function]

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