Mouse Vapa activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vapa
Locus ID	30960
Kit Components	GA205310G1, Vapa gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205310G2, Vapa gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205310G3, Vapa gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013933, NM_001355402
Synonyms	33kDa; VAP33
Summary	Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking.[UniProtKB/Swiss-Prot Function]

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